Daniel Sturridge has been ruled out of England's opening Euro 2016 qualifier against Switzerland on Monday.
The Liverpool man pulled up during Friday's training session at St. George's Park.
An FA Spokesman said: “Daniel Sturridge picked up an injury on his thigh in training.
"He has had a scan and will now return to Liverpool FC for treatment. He will play no part in the forthcoming Switzerland match.”
England manager Roy Hodgson has not called up a replacement at this time.