Manager Dave Edmondson has left FA WSL 1 side Bristol Academy with the club bottom of the table.
The Vixens have lost all three League matches so far this season.
They were also knocked out of The FA Women’s Cup at the fifth round stage by Everton.
Bristol Academy chairman Simon Arnold said: “I think it is clear to everyone, we had started to lose our way and despite Dave’s efforts we were seeing a decline in areas which need to be addressed sooner rather than later.
“It was a difficult decision for us as he is an honest, hardworking and talented coach but sometimes things just don’t happen the way you want them to and we have no choice but to make a change.
"Dave goes with our thanks and we wish him all the very best in the future. We will now begin the task of selecting a successor and an announcement will take place when this has been completed.”
Assistant first team coach, Lauren Smith will take over as interim head coach until a new manager has been appointed.
Bristol entertain Notts County on Saturday at Stoke Gifford Stadium with both sides looking for their first League win of the campaign.