The 28-year-old led the Lionesses out for their final match of the Dewellbon Cup, with Isobel Christiansen’s second-half strike sealing the victory.
Scott said: "It’s a very special day. Probably one of the best days of my life.
England 1-0 Australia
The Dewellbon Cup
Tuesday 27 October 2015
Yongchuan, China
"I’d like to thank the team and the staff for making it such a special day for me and my family and friends.
"It’s definitely a day to remember and treasure."
The Manchester City midfielder made her debut against Holland in August 2006 and has gone on to play at two European Championships and three World Cups, helping England to win silver at Euro 2009 and bronze at Canada 2015.
And she is only the ninth Women’s player to reach triple figures.
The former Sunderland and Everton star added: "I knew it was approaching after the World Cup and I’m just absolutely delighted to get 100 caps and join the fantastic names that have already reached [the landmark]; Casey Stoney, Rachel Yankey and Fara Williams are just a few.
"I can’t believe I’m in the ‘100 Club’."
VIDEO: @JillScott12 on a "very proud day" as she won her 100th cap in the #Lionesses 1-0 win over Australia https://t.co/6o7DSuKPTX
— England (@england) October 27, 2015
Scott’s first appearance at a senior tournament was the 2007 World Cup in China – the country where she would eventually reach the 100 mark.
She also took a moment to thank two former coaches who helped her on her journey.
Scott added: "My first competitive tournament was in China so it’s a bit mad how things come back around.
"I turned up at the 2007 World Cup, I only had a few caps but Hope Powell gave me the chance to go out on the world stage and have a go.
"I played about 75 times under Hope and I owe her a lot. Mo Marley gave me my first chance at U19s level so I owe her a lot too."
As well as her 100th cap, Scott was also pleased to be leaving China with a notable win against the World Cup quarter finalists, following Friday’s 2-1 defeat by the host nation.
She said: "We needed this win today. We didn’t want to leave China having not won a game.
"We competed very well and there were a lot of positives we can take from the game. I thought Demi Stokes was fantastic and as a team I think we stuck to the plan and it was a great finish by Izzy to win it."
England’s next assignment is an away friendly against European champions Germany on 26 November, three days before they entertain Bosnia & Herzegovina at Bristol City FC.
Tickets for the Bosnia game are on sale now priced £5 for adults and £2.50 for children. A family ticket (two adults and two children) is available at £10 and group booking discounts apply.
Tickets can be purchased via TheFA.com/Ticketsy or by calling 01179 630 600.