In the Northern Premier, Coventry are looking to extend their lead with a visit to second-bottom Nottingham Forest, whilst second-placed Sheffield FC have a tough home game against Bradford City.
Blackburn Rovers face a strong home test against Stoke whilst Huddersfield will host Sporting Club Albion. In the bottom half, Newcastle face Derby at home and Wolves will be seeking additional points away to Preston.
In the Southern Premier, leaders Cardiff face a trip to QPR, with Portsmouth leading the chasing pack by hosting West Ham. Third meets fourth with Brighton hosting Charlton and Tottenham face a trip to Gillingham.
In the bottom half of the table, Keynsham are currently pointless and host Lewes whilst Plymouth will take on Copsewood.
There is no league programme this weekend for the Division One clubs as they enter The FA Women’s Cup.
In the North, Middlesborough are away to Blackpool Wren Rovers, whilst Chorley entertain Tynedale. Norton & Stockton play host to Midlands Div 1 team Curzon whilst Guiseley AFC host Peterlee. Chester le Street travel to Hull City, whilst the only tie featuring two teams from the Division takes place between Leeds FC and Tranmere Rovers. Mossley are away to Midlands Division team Steel City and the final game sees Stockport County hosting Accrington.
Mansfield host Solihull in the Midlands region, with Leicester City LFC travelling to Burton Park. Loughborough Students travel to Crewe whilst Leicester City WFC entertain Crusaders. Radcliffe Olympic host Ellistown with Rotherham hosting Sheffield Wednesday. Leafield Athletic travel to The New Saints and FC Reedswood and Mansfield host Burton Albion and Billbrook respectively.
Further south – leaders C&K Basildon entertain Barking, with Crystal Palace hosting AFC Wimbeldon. MK Dons are away to Bar Hill and Cambridge travel to Wymondham. Ipswich entertain near neighbours Colchester whilst Norwich have an interesting game at home to Lowestoft. Luton travel to Leighton United whilst Denham travel to London Corinthians.
Finally in the South West, leaders Forest Green entertain Oxford City with second placed Southampton Saints hosting Swindon Spitfires. Exeter City travel to Parley Sports and Cheltenham play their fellow league team St Nicholas at home. Shanklin make the long journey to Maidenhead whilst Gosport travel the coast to fellow sea-siders Eastbourne. The final game sees Larkhall host Bridgewater.