Gavan Holohan's heroics helped haul League Two Grimsby Town to a stunning Emirates FA Cup upset against Premier League Southampton.
The Irish striker netted a pair of penalties at St Mary's to fire the Mariners to the biggest shock of the midweek fifth round clashes.
Duje Caleta-Car pulled one back for Ruben Selles' hosts but Grimsby, currently sat 16th in the fourth-tier table, remarkably held on to continue their cup adventure on the south coast.
Southampton looked threatening throughout the opening period but it was the underdogs who snatched the lead on the cusp of half-time.
Saints defender Lyanco handled after good work from Danilo Orsi and, following a lengthy VAR delay, referee Thomas Bramall pointed to the spot.
It's all going off in Southampton for @officialgtfc 🥳🤣#EmiratesFACup pic.twitter.com/Baq8JmSCim
— Emirates FA Cup (@EmiratesFACup) March 1, 2023
Holohan stepped up with ice-cool nerves to roll the ball past Alex McCarthy and send the loyal travelling contingent into raptures at the far end.
That left Southampton with work to do at the break but Grimsby doubled their advantage in identical circumstances just five minutes after the restart.
Orsi, whose good work helped engineer the visitors' opener, went down in the box and Holohan took full advantage of the subsequent spot-kick to fire home into the top corner and give the top-flight hosts a mountain to climb.
Southampton did pull one back just after the hour mark when Caleta-Car, who conceded the second penalty 15 minutes earlier, volleyed home at the far post from James Ward-Prowse's cross.
But the Mariners held on to stun Selles' newly-inherited side and trigger ecstasy in the Grimsby away end, whose fans had made the mammoth 240-mile trip from Lincolnshire down to Hampshire on Wednesday night.
In another significant fifth round upset, Iliman Ndiaye’s late winner helped Championship side Sheffield United stun in-form Tottenham Hotspur at Bramall Lane.
The intriguing clash looked to be heading towards extra-time before Senegalese ace Ndiaye jinked his way through the Spurs defence in mesmerising fashion to rifle home into the bottom corner.
Here's your full draw for the #EmiratesFACup quarter-final 👇
— Emirates FA Cup (@EmiratesFACup) March 1, 2023
Manchester United completed a frantic late turnaround to triumph in their all-Premier League tie against West Ham United.
Said Benrahma opened the scoring for David Moyes’ - returning to his former club - visitors at the start of the second half to put the Hammers on the verge of progression at Erik ten Hag’s red-hot hosts.
But Nayef Aguerd's own goal levelled the scores before strikes from Alejandro Garnacho and Fred turned the tables in stoppage-time to help United keep their hopes of winning four major trophies this season alive.
Elsewhere, Connor Roberts’ dramatic late winner fired Championship table-toppers Burnley to a 1-0 win over League One Fleetwood Town.
Scott Brown’s underdogs delivered a defiant performance at Turf Moor but were dealt a bitter blow at the death when Welsh star Roberts struck on St David’s Day to propel the Clarets into the quarter-finals.