The West Brom goalkeeper, a regular in the England squad, was forced to leave the field in the second half with a knee injury during the Baggies’ 1-0 win over Stoke City, with Saido Berahino also playing for Albion.
There were no such worries for the Three Lions of Arsenal as Calum Chambers, Theo Walcott and Danny Welbeck all played their part in helping the Gunners maintain their challenge for a top four finish with a 3-0 win over West Ham.
Welbeck almost got his name on the scoresheet with a late header which saw West Ham keeper Adrian produce a fine save to his left.
Another England goalkeeper did not have a happy Saturday as Joe Hart's Manchester City side went down 1-0 against Burnley at Turf Moor - U21s striker Danny Ings was upfront for the Clarets.
Elsewhere, Fabian Delph helped Aston Villa to a thumping victory over Sunderland at the Stadium of Light as a brace apiece for Christian Benteke and Gabriel Agbonlahor sealed a 4-0 win. Rushian Hepburn-Murphy, who represented the Young Lions at U17s level, came off the bench for Villa to make his senior debut.
And Wilfried Zaha, who has two senior caps for England, was among the scorers as Crystal Palace secured a 3-1 win over QPR at Selhurst Park.
Under-21s boss Gareth Southgate will be a happy man this weekend as a number of his Young Lions showed their goalscoring credentials in the Championship.
Patrick Bamford, on-loan from Chelsea, struck twice for Middlesbrough as they romped to a 4-1 home win over Ipswich Town in the lunchtime kick off.
The result briefly lifted Boro into top spot, but they were overtaken by Bournemouth on goal difference later in the day.
Another of Southgate’s strikers, Callum Wilson, netted from the spot as the Cherries defeated Blackpool 4-1 on the south coast.
Lewis Cook, an England U18s international, played the full ninety minutes for Leeds United as they drew 0-0 with Nottingham Forest.
His international team-mate Sheyi Ojo, on-loan from Liverpool, helped Wigan Athletic take a step closer to safety with a 2-1 win at Rotherham United.
And moving down to League One, England U20s captain Lewis Baker featured for MK Dons in their 1-1 draw at Walsall whilst another of Aidy Boothroyd’s men, Ben Pearson, helped Barnsley to record a 3-1 win away to Oldham.